Leukaemic synovitis

Leukaemic meningitis.

Patients with leukaemia now live longer and have greater opportunity to develop complications both due to therapy and to the disease itself. The treatment of leukaemic infiltration of the meninges has received little attention in this country, possibly because it has been regarded as a terminal event in a fatal disease. This is not necessarily true. Intracranial complications of acute leukaemia...

Cytochemistry of leukaemic lymphoid cells.

Acute leukaemic conditions in childhood.

In any age group the leukaemic state is characterized by overgrowth of the leucopoietic tissues, in which an increased number of leucocytes, many of which are immature, rapidly develop. These young white cells are also found among the greatly increased total number of leucocytes in the circulating blood and it is on their presence and their type that the diagnosis depends. Occasionally, however...

Normal and leukaemic stem cells.

The blood-related cancer leukaemias were the first diseases where human cancer stem cells, or leukaemic stem cells (LSC), were isolated. The haematopoietic system is one of the best tissues for investigating cancer stem cells, because the developmental hierarchy of normal blood formation is well defined. Leukaemias can now be viewed as aberrant haematopoietic processes initiated by rare LSC tha...

Starch synovitis.

Three patients with unexplained synovial inflammation were found to have an ulcerative, granulomatous synovitis on biopsy. Maize starch was identified in giant cells within the granulomata. Starch synovitis has clinical and histological similarities to starch peritonitis, which is thought to be an example of a cell mediated immune response.